Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
FGF2 | P09038 | fibroblast growth factor 2 | Signaling | 1.8E-02 | 0.383 | 0.923 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
SST | P61278 | somatostatin | Signaling | 0.34 | 0.399 | 0.885 |
PTH | P01270 | parathyroid hormone | 1.2E-02 | 0.397 | 0.846 | |
CASR | P41180 | calcium sensing receptor | G-protein coupled receptor | 4.7E-02 | 0.410 | 0.846 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
CALCA | P01258 P06881 | calcitonin related polypeptide alpha | Signaling | 1.6E-02 | 0.416 | 0.923 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
SPG7 | Q9UQ90 | SPG7 matrix AAA peptidase subunit, paraplegin | Enzyme | 2.0E-36 | 0.436 | 0.885 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
GDNF | P39905 | glial cell derived neurotrophic factor | Signaling | 0.20 | 0.434 | 0.885 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
MEN1 | O00255 | menin 1 | 1.00 | 0.444 | 0.808 | |
SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |
PSMD9 | O00233 | proteasome 26S subunit, non-ATPase 9 | Enzyme modulator | 4.9E-06 | 0.435 | 0.846 |